Our primary CC is the GM MasterCard because it pays 5%. However the reward is limited to a max of $500/year, so once you've charged $10,000 in the year, there's no more rewards applied until the next year. That's when we switch all our charges to the Disney Visa and get the 1%.
The secret is of course that you MUST pay off the entire balance each and every month. We do this without fail. If you wind up paying interest on a credit card just once, you've probably negated any rewards you've earned.
We charge absolutely everything to the card, including groceries, gas, satellite (TV), internet (annual), cell phone, house insurance, car insurance, merchandise, etc, but we don't charge anything which adds a handling fee (such as home property taxes where they will accept the cards but the card holder charges about 3% fee)
If we make a major purchase on the card (perhaps $2000-$3000) one month, then we will write a home equity loan check to still pay the credit card in full, and pay off the home equity loan (about 4.5% APR) over the next few months.